Mesotherapy — RRS Skin Biorevitalisation

Mesotherapy at Estetická klinika Hradec Králové delivers customised cocktails of hyaluronic acid, vitamins, antioxidants, peptides, minerals and phospholipids directly into the middle layer of skin via micro-injections, targeting hydration, skin renewal and early anti-ageing from within. The clinic uses the RRS product line — a premium Spanish biorevitalisation brand — and treats the face (from 3 500 Kč) and the delicate under-eye area (from 1 900 Kč), with a recommended course of 3–4 sessions spaced 3–4 weeks apart.

Mesotherapy is a technique founded in France in the 1950s, in which micro-doses of active substances are injected precisely into the mesoderm (the middle skin layer, the dermis) rather than topically applied where penetration is limited. At Estetická klinika Hradec Králové, the chosen product line is RRS — a European-registered brand of biorevitalisation cocktails formulated with cross-linked and free hyaluronic acid in combination with vitamins (C, B-complex), amino acids, minerals, coenzymes and antioxidants. Each component addresses a specific aspect of skin ageing: HA provides hydration and volume support, vitamins accelerate cell turnover, amino acids supply the building blocks for collagen and elastin synthesis, antioxidants neutralise oxidative stress. The under-eye zone — among the most delicate and earliest to show ageing — is addressed with a specific RRS eye-area protocol from 1 900 Kč. Facial treatment covers a broader zone from 3 500 Kč. Sessions take 30–45 minutes. A small needle (the same gauge as an insulin syringe) is used to make multiple shallow injections in a grid or nappage pattern across the treatment zone. Topical anaesthetic cream can be applied beforehand for comfort, though most patients tolerate the procedure without it. Immediate post-treatment effects include mild redness and small injection papules that resolve within a few hours. In the days following, the skin absorbs the active substances and begins responding — patients typically notice improved hydration and luminosity from the first week. The cumulative effect of 3–4 sessions produces meaningful improvement in skin tone, texture, fine lines and elasticity. Maintenance sessions every 3–6 months sustain results. The treatment is often combined with microneedling or PRP at the clinic for a synergistic collagen-stimulation response.