


Type
Mesotherapy
Duration
30 min
What's included
3 deliverables in this treatment
- Consultation and assessment of skin quality
- Injection of the polynucleotide bio-stimulator via fine needle
- Aftercare and sun-protection guidance
An injectable bio-stimulator that uses purified polynucleotides — fragments of DNA — to trigger deep skin regeneration rather than simply adding volume. Once injected, the polynucleotides act as a scaffold and signal that stimulates cell renewal, hydration and tissue repair. At this Brno dermatology practice they are used to rejuvenate the face, neck, décolletage and hands and to nourish the scalp for hair, making them a good option for thin, fragile or tired skin that needs strengthening rather than filling.
About this treatment
Polynucleotides are highly purified chains of DNA fragments, typically derived from natural sources, that work as a regenerative bio-stimulator rather than a conventional filler. When injected into the skin they form a hydrating gel-like scaffold and, more importantly, signal the surrounding cells to renew themselves — boosting fibroblast activity, improving hydration, supporting the skin's own collagen and elastin production and aiding tissue repair. At…
Good to know
- Active
- Purified polynucleotide (DNA-fragment) bio-stimulator
- Action
- Stimulates cell renewal and regeneration
- Common areas
- Face, neck, décolletage, hands, scalp
Who is this for?
Thin, crêpey or fatigued skin needing regeneration; face, neck, décolletage and hand rejuvenation; hair nourishment
Preparation required
Avoid blood thinners and alcohol beforehand to limit bruising. Arrive with clean, make-up-free skin.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
23 clinic reviews
From independent platforms
Clinical team
The practice is led by two board-certified physicians. MUDr. Iveta Hrabálková graduated from the Masaryk University Faculty of Medicine in Brno in 1991, holds first-degree (1994) and second-degree (1999) certification in dermatovenereology, and spent 18 years in the dermatology department of Brno University Hospital before opening her private aesthetic practice in 2008. Her aesthetic-medicine training (GHC Clinic…
Clinic-reported credentials
Languages: Czech
What clients say
"The doctor is excellent, along with the nurse. Everything is explained and advised — a professional, humane and kind approach. I felt very good there and left satisfied."
"Dr. Hrabálková is cultured and a quality physician. I'd recommend her especially to women dealing with various aesthetic skin problems."
Treatment highlights
- Consultation and assessment of skin quality
- Injection of the polynucleotide bio-stimulator via fine needle
+1 more item in What's included
From 1,500 Kč per treatment. A course is usually recommended for cumulative regeneration; price set at consultation by the area treated. Often used for face, neck, décolletage, hands and the scalp for hair nourishment.

