Polynucleotides

An injectable bio-stimulator that uses purified polynucleotides — fragments of DNA — to trigger deep skin regeneration rather than simply adding volume. Once injected, the polynucleotides act as a scaffold and signal that stimulates cell renewal, hydration and tissue repair. At this Brno dermatology practice they are used to rejuvenate the face, neck, décolletage and hands and to nourish the scalp for hair, making them a good option for thin, fragile or tired skin that needs strengthening rather than filling.

Polynucleotides are highly purified chains of DNA fragments, typically derived from natural sources, that work as a regenerative bio-stimulator rather than a conventional filler. When injected into the skin they form a hydrating gel-like scaffold and, more importantly, signal the surrounding cells to renew themselves — boosting fibroblast activity, improving hydration, supporting the skin's own collagen and elastin production and aiding tissue repair. At Estetická dermatologie MUDr. Hrabálková they are used to rejuvenate and strengthen the face, neck, décolletage and hands, and to nourish the scalp as part of a hair-support plan; the clinic highlights their strong regenerative effect and ability to stimulate cell renewal. A treatment takes roughly 20 to 30 minutes: after cleansing, the physician injects the polynucleotide solution into the target area through a fine needle in a pattern suited to the concern. Because the benefit comes from stimulating the skin's biology, polynucleotides are typically given as a short course of sessions for cumulative effect, with results developing gradually over the following weeks as skin quality, firmness and hydration improve. Downtime is minimal — small injection marks, occasional mild swelling or bruising that settle within a few days, and the usual requirement for sun protection afterwards. Polynucleotides particularly suit people with thin, crêpey, dehydrated or fatigued skin who want regeneration and quality improvement rather than added volume, as well as those seeking a gentle option for the delicate eye area, neck and hands. They are avoided during pregnancy and breastfeeding, over active infection, and in people with bleeding disorders or relevant allergies; suitability and the treatment plan are confirmed at the consultation.