DNA Rejuvenation (Salmon Polynucleotides)

DNA rejuvenation uses polynucleotides derived from purified salmon DNA, injected into the skin to stimulate regeneration, deep hydration and the production of collagen and elastin for improved firmness. It is a gentle microinjection treatment for the face, neck, décolletage and the delicate eye contour, with optional numbing cream for comfort. At Estéea it is offered as a short course of two to four treatments, with results that build over the following weeks and last several months.

DNA rejuvenation is a regenerative skin treatment based on polynucleotides — fragments of highly purified DNA, in this case sourced from salmon, which are biocompatible with human tissue. When injected into the skin, polynucleotides act as a scaffold and a signal: they hydrate deeply, scavenge free radicals, and stimulate fibroblasts to produce fresh collagen and elastin. The effect is improved skin quality, firmness and elasticity rather than added volume, which makes it especially useful for thin, fragile or tired skin, including the delicate eye contour where stronger fillers are unsuitable. At Estéea the treatment is delivered through gentle microinjections across the target area — face, neck, décolletage or under-eye contour — with a numbing cream available beforehand for comfort. A session takes around thirty to forty-five minutes. Downtime is minor: small injection marks, redness or slight swelling that typically resolve within one to two days. Because regeneration is gradual, the recommended protocol is a course of two to four treatments spaced a few weeks apart, after which the improvement lasts several months before maintenance is considered. DNA rejuvenation suits adults wanting to improve overall skin quality, firmness and hydration, and is a good option for areas too delicate for conventional fillers. Suitability and any contraindications are reviewed at consultation; as with other injectables it is avoided during pregnancy and breastfeeding, and those with a fish allergy should disclose it given the salmon-derived source.