Nucleofill Polynucleotide Skin Stimulator

Nucleofill is a polynucleotide-based injectable that bio-stimulates and hydrates the skin, improving elasticity, texture and firmness. Dedicated formulations target the lower face and the delicate skin around the eyes, where a Soft Eyes version helps with crêpey texture and dark, tired-looking under-eyes. The clinic delivers it by physician injection as a short course, suiting patients who want healthier, more resilient skin.

Nucleofill is a skin bio-stimulator based on polynucleotides — long chains derived from purified DNA fragments — that hydrate the tissue and support the skin's own regenerative processes. It is used to improve elasticity, texture, firmness and overall skin quality, and is associated with a gradual freshening of tired skin rather than an immediate change in volume. Different formulations are matched to the area: Nucleofill Medium and Phil Art for the face, and Nucleofill Soft Eyes for the thin, delicate skin of the periorbital area, where it can help with crêpiness and a tired under-eye appearance. At the clinic of dr Katarzyna Wojtarowicz the physician places a series of small injections into the target area; a session takes around twenty to thirty minutes, with optional numbing for comfort. Downtime is minimal — small bumps and pinpoint marks settle over hours to a day or two. Because the effect builds as the skin responds, Nucleofill is commonly associated with the best results as a short course of sessions spaced a few weeks apart, followed by maintenance. It suits adults wanting better skin quality, more resilience and improvement in the eye area, and it can be combined with mesotherapy, Profhilo and other treatments the clinic offers. Suitability and contraindications, including for the eye area, are reviewed by the doctor before starting; it is avoided during pregnancy and breastfeeding.