NAD+ IV Drip

A high-dose nicotinamide adenine dinucleotide (NAD+) infusion delivered intravenously over approximately two hours. NAD+ is a coenzyme present in every living cell that plays a central role in energy metabolism, DNA repair, and sirtuin activation. Levels decline with age, and IV supplementation delivers the molecule directly into the bloodstream at concentrations that oral NAD+ precursors cannot replicate.

Nicotinamide adenine dinucleotide (NAD+) is one of the most researched molecules in the longevity and cellular health space. It functions as an electron carrier in the mitochondrial electron transport chain, making it essential for converting nutrients into cellular energy. Beyond energy metabolism, NAD+ activates sirtuins — a family of proteins involved in DNA repair, epigenetic regulation, and inflammatory response modulation — and serves as a substrate for PARP enzymes that repair single-strand DNA breaks. NAD+ levels decline measurably with age. Research in animal models has shown that restoring NAD+ levels can improve mitochondrial function, enhance insulin sensitivity, and extend markers associated with healthspan. While human clinical data is still building, the mechanistic rationale for NAD+ supplementation is well-established across hundreds of published studies. The IV route is preferred for NAD+ because oral precursors like NMN and NR must pass through the liver and undergo conversion before reaching target tissues, losing bioavailability at each step. Intravenous delivery bypasses this cascade entirely, achieving plasma and tissue concentrations that the oral route cannot match. The trade-off is time: NAD+ infusions are administered slowly to manage the flushing and chest warmth that can occur with faster drip rates. A typical session at DNA Health & Wellness runs about two hours. During the infusion, patients rest in the clinic's IV suite. Staff monitor comfort and adjust drip speed if the patient experiences any warmth or tingling, which is a normal physiological response that subsides as the rate is modulated. Most recipients describe the post-session experience as heightened mental clarity, improved focus, and a general sense of restored energy that can persist for several days to a week. The clinic recommends an initial series of sessions spaced one to two weeks apart, followed by monthly maintenance infusions for those seeking ongoing support. NAD+ drips pair well with the clinic's health screening packages, which can establish baseline metabolic and inflammatory markers to track the impact of supplementation over time.