e-Pakiet Hashimoto

Dedicated Hashimoto thyroiditis panel with 13 markers combining thyroid function (TSH, fT3, fT4), autoimmune antibodies (anti-TPO, anti-TG), inflammation (CRP), haematology (CBC), and nutritional cofactors critical for thyroid health (selenium, vitamin D3, B12, iron, ferritin, magnesium). At 368 PLN (~85 EUR) with blood draw included.

This panel goes beyond standard thyroid assessment by integrating the nutritional cofactors that directly influence thyroid function and autoimmune disease progression. Hashimoto thyroiditis is the most common autoimmune disease worldwide, affecting up to 10% of women, and its management increasingly recognises the role of micronutrient status. The thyroid function core (TSH, fT3, fT4) monitors the hypothalamic-pituitary-thyroid axis. In Hashimoto disease, progressive thyroid destruction manifests first as subclinical hypothyroidism (elevated TSH with normal fT4) before progressing to overt hypothyroidism (elevated TSH with low fT4). Monitoring both free hormones tracks disease progression and guides levothyroxine dosing. Anti-TPO and anti-TG antibodies confirm the autoimmune aetiology. Antibody titres do not directly correlate with disease severity, but declining titres on treatment suggest reduced autoimmune activity. Some clinicians track antibody levels as a marker of dietary and lifestyle intervention effectiveness. Selenium is a critical inclusion. The thyroid gland contains more selenium per gram of tissue than any other organ. Selenoproteins are essential for thyroid hormone synthesis (deiodinases convert T4 to active T3) and for protecting thyroid cells from oxidative damage. Multiple randomised trials have demonstrated that selenium supplementation (200 mcg daily) reduces anti-TPO titres in Hashimoto patients. Poland lies in a selenium-poor geological zone, making deficiency common. Vitamin D3 deficiency is strongly associated with autoimmune thyroid disease in epidemiological studies. Patients with Hashimoto have significantly lower vitamin D levels than matched controls. While causality is debated, maintaining levels above 30 ng/mL (75 nmol/L) is recommended by most endocrinologists managing autoimmune thyroid disease. Vitamin B12 deficiency coexists with autoimmune thyroid disease at elevated rates — both conditions share HLA genetic risk variants, and pernicious anaemia (autoimmune B12 malabsorption) occurs in 5-10% of Hashimoto patients. Iron and ferritin assess iron stores, which are essential for thyroid peroxidase function — iron deficiency impairs thyroid hormone synthesis independent of TSH. Magnesium is a cofactor in over 300 enzymatic reactions including thyroid hormone metabolism. CRP provides inflammation monitoring, and the CBC screens for anaemia — a common consequence of the nutritional deficiencies this panel investigates. At 368 PLN with blood draw included, this holistic Hashimoto assessment would cost 400-800 EUR at a German endocrinology practice.