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Practitioner with IPL/laser handpieces beside a laser device and touchscreen console
Founder and clinic director MUDr. Zuzana Vykutilová

Rejuran (Polynucleotide Skin Rejuvenation)

Type

Mesotherapy

Duration

45 min

What's included

4 deliverables in this treatment

  • Skin assessment
  • Numbing cream
  • Polynucleotide micro-injections over the agreed area
  • Aftercare guidance

Rejuran is a skin-rejuvenation treatment using polynucleotides — natural DNA chains derived from salmon — injected into the skin to support the renewal of skin cells, improve elasticity and firmness and stimulate collagen and elastin. At Dermaestet it is offered for the face under numbing cream and is one of the current trends in aesthetic medicine, aimed at brightening, regenerating and smoothing fine lines and uneven texture. Results build progressively, so it is usually given as a course for the most visible improvement.

About this treatment

Rejuran is a regenerative skin treatment based on polynucleotides — long chains of nucleotides, the building blocks of DNA, purified from salmon. When injected into the skin, polynucleotides act as a biological signal that supports the natural renewal of skin cells, improves hydration and elasticity and stimulates the production of collagen and elastin, leading to overall brightening, regeneration and a marked improvement in the firmness and texture of…

A session takes around thirty to sixty minutes and is performed under a numbing cream for comfort, with a series of fine micro-injections across the area; the clinic offers a standard facial area and a larger area. Afterward there may be small temporary bumps at the injection points, mild redness or minor bruising that settle within a day or two. Because the benefit is regenerative and cumulative, Rejuran is typically delivered as a course of sessions…

Good to know

Active
Polynucleotides (salmon DNA)
Targets
Cell renewal, elasticity, texture
Best as
A course

Who is this for?

Adults wanting genuine skin-quality renewal — smoother, firmer, more even skin

Preparation required

Attend with clean skin and avoid alcohol and blood thinners for a day or two. Disclose any fish allergy.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

Dermaestet clinical team

Clinical team

Dermaestet is led by founder and clinic director MUDr. Zuzana Vykutilová, a dermatovenerologist and aesthetic-medicine specialist. The medical team includes dermatovenerologists MUDr. Michaela Juráková (also lasers), MUDr. Zuzana Jelínková, Ph.D., MUDr. Eliška Jugová and MUDr. Nela Pelánková; MUDr. Linda Rozsypalová in aesthetic medicine and laser treatments; MUDr. Michaela Bártová for minor surgery; plastic surgeon…

Clinic-reported credentials

Czech Ministry of Health accredited training centre (dermatovenerology and corrective dermatology)

Languages: Czech, English

What clients say

"The result exceeded my expectations. Overall a very good experience. (Petr Juračka, ZnámýLékař)"

"Dermaestet is the best clinic in Brno; you'll find a sensitive, almost familial approach from the whole team. (Dagmar Š.)"

View the full Dermaestet profile
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