Rejuran (Polynucleotide Skin Rejuvenation)

Rejuran is a skin-rejuvenation treatment using polynucleotides — natural DNA chains derived from salmon — injected into the skin to support the renewal of skin cells, improve elasticity and firmness and stimulate collagen and elastin. At Dermaestet it is offered for the face under numbing cream and is one of the current trends in aesthetic medicine, aimed at brightening, regenerating and smoothing fine lines and uneven texture. Results build progressively, so it is usually given as a course for the most visible improvement.

Rejuran is a regenerative skin treatment based on polynucleotides — long chains of nucleotides, the building blocks of DNA, purified from salmon. When injected into the skin, polynucleotides act as a biological signal that supports the natural renewal of skin cells, improves hydration and elasticity and stimulates the production of collagen and elastin, leading to overall brightening, regeneration and a marked improvement in the firmness and texture of the skin. Unlike a conventional filler, Rejuran works at the level of skin quality and cell renewal rather than adding volume, and at Dermaestet it is presented as a modern treatment using salmon-derived DNA that ranks among the current trends in aesthetic medicine. A session takes around thirty to sixty minutes and is performed under a numbing cream for comfort, with a series of fine micro-injections across the area; the clinic offers a standard facial area and a larger area. Afterward there may be small temporary bumps at the injection points, mild redness or minor bruising that settle within a day or two. Because the benefit is regenerative and cumulative, Rejuran is typically delivered as a course of sessions spaced a few weeks apart, with results — smoother texture, more even tone, improved elasticity and softened fine lines — building over the following weeks. It suits adults wanting genuine skin-quality renewal, including for dull, tired or crepey skin. Allergies and suitability (including any sensitivity to fish-derived products) are checked first, it is avoided during pregnancy and breastfeeding, and results develop gradually.