Longevity.haus
HydraFacial treatment in progress — wide banner shot
HydraFacial device handpiece — treatment room equipment
DermaPen microneedling device close-up
Staff operating laser equipment in clinical setting
MUDr. Michal Sičák — founder and medical director

Vitiligo Treatment — Excimer Laser, DermaPen and PRP

Type

Laser

Duration

2 hours

What's included

5 deliverables in this treatment

  • Venous blood draw and PRP centrifuge preparation
  • DermaPen microneedling of depigmented patches with PRP infusion
  • Two-week healing pause between microneedling and laser stages
  • XTRAC 308 nm excimer laser sessions (3–5 per week for 3 weeks per cycle)
  • Cycle progress review before each repeat cycle

A three-modality combined protocol for vitiligo using DermaPen microneedling plus PRP, followed by XTRAC 308 nm excimer laser — addressing both the loss of melanocytes and the underlying autoimmune suppression of melanogenesis. The DermaPen creates micro-channels that allow activated PRP growth factors to reach melanocyte progenitors in the hair follicle bulge; the excimer laser then destroys the T-lymphocytes responsible for autoimmune melanocyte killing and stimulates surviving melanocytes to repopulate the depigmented zone. One complete five-week cycle encompasses all three stages; a minimum of five cycles is recommended.

About this treatment

Vitiligo is an autoimmune condition in which T-lymphocytes aberrantly target and destroy melanocytes — the pigment-producing cells of the epidermis — resulting in well-demarcated, depigmented patches. Repigmentation requires two simultaneous achievements: suppression of the autoimmune attack to prevent continued melanocyte destruction, and stimulation of surviving melanocyte progenitors in the hair follicle reservoir to migrate and repopulate the…

Derma Medical Clinic's combined vitiligo protocol addresses both requirements in sequence. The first stage is a DermaPen microneedling session over the depigmented patches: the micro-channels created by the needles extend through the epidermis into the dermis, transiently disrupting the barrier that ordinarily restricts the migration of hair follicle–resident melanocyte stem cells. Immediately after needling, activated PRP (platelet-rich plasma) is…

This completes one five-week cycle. The cycle is repeated; clinical data at Derma Medical Clinic and in the published literature suggest a minimum of five complete cycles for meaningful repigmentation, with response rates varying significantly by patch location — face, trunk and genitalia respond most readily, while hands and feet require more sessions. Session duration for each cycle stage ranges from the DermaPen and PRP session (approximately two hours…

Good to know

Protocol
DermaPen + PRP, then XTRAC laser — 5-week cycles
Minimum cycles
5 complete cycles recommended
Best response areas
Face, trunk, genitalia (hands/feet need more cycles)
Mechanism
Autoimmune suppression + melanocyte progenitor stimulation

Who is this for?

Adults with stable or slowly progressive vitiligo on face, trunk or other body areas seeking structured repigmentation; patients motivated to complete a full multi-cycle protocol

Preparation required

Eat normally before PRP sessions. Avoid aspirin and blood-thinning supplements for 5 days before each cycle. Do not tan the affected areas during the course. Inform the physician of any immunosuppressive medications.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

Derma Medical Clinic clinical team

Clinical team

Derma Medical Clinic was founded by MUDr. Michal Sičák, a physician with a background in cardiology and pharmaceutical management spanning the Czech Republic, Saudi Arabia, the USA and Ukraine. Before opening the first clinic in 2013, MUDr. Sičák ran a company supplying aesthetic medicine technologies to clinics across the Czech Republic, Slovakia and Poland. He introduced the XTRAC excimer laser to Czech clinical…

Languages: Czech

What clients say

"The psoriasis laser treatment worked where creams had failed for years. After ten sessions my skin was clear for the first time in a decade. — Patient review via clinic press coverage, Vitalia.cz"

"The HydraFacial gave immediate results — my skin was visibly brighter straight after the first session. Very professional team. — Patient review via clinic press coverage, Blesk.cz"

View the full Derma Medical Clinic profile
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