Botulinum Toxin — Wrinkle Smoothing

Botulinum toxin works by blocking the presynaptic release of acetylcholine at the neuromuscular junction. When a precisely calibrated dose is deposited into a specific facial muscle, the chemical signal that triggers contraction is interrupted: the muscle relaxes, and the skin overlying it stops folding repetitively with each expression. The underlying dermal structure is unaffected; lines soften because the mechanical creasing that reinforces them has…

At Derma Medical Clinic Ústí nad Labem each botulinum toxin session begins with a physician assessing the patient's facial dynamics: how the forehead lifts, where frown-line muscles engage, the distribution of periorbital creasing when smiling. This mapping guides injection point placement, depth and the dose per muscle. Ultra-fine needles are used throughout; topical numbing cream is applied beforehand for patients who prefer it. The injection sequence…

Common treatment areas include the glabella (the vertical frown lines between the eyebrows, produced by the corrugator and procerus muscles), the forehead (frontalis muscle, horizontal lines), the lateral canthal lines (crow's feet, orbicularis oculi), upper lip lines, chin bunching and brow shaping. Combinations of areas are often treated in the same session. The full effect becomes visible at ten to fourteen days, at which point a brief follow-up…