Type
Genetic Testing
Duration
30 min
Sample
Amniotic fluid or chorionic villi
What's included
3 deliverables in this treatment
- Laboratory analysis of amniotic fluid or chorionic villus sample
- Choice of QF-PCR rapid aneuploidy detection, full karyotype, or microarray
- Written diagnostic laboratory report
For pregnancies undergoing invasive sampling (amniocentesis or chorionic villus sampling), the laboratory provides diagnostic chromosomal analysis of the fetal sample. Options range from rapid QF-PCR detection of the most common aneuploidies through to a full fetal karyotype and high-resolution microarray analysis for microdeletion and microduplication syndromes. These are confirmatory diagnostic tests, typically performed after a high-risk screening result or on clinical indication.
About this treatment
When invasive prenatal sampling is performed — amniocentesis (amniotic fluid) or chorionic villus sampling — the fetal material is sent to the laboratory for chromosomal analysis. Several complementary methods are offered.
QF-PCR (quantitative fluorescence PCR) provides a rapid result, often within a day or two, for the common aneuploidies. The laboratory offers a single-target chromosome 21 assay and a broader panel covering chromosomes 13, 18, 21, X and Y — the chromosomes responsible for the most frequent and clinically significant aneuploidy syndromes.
Full karyotyping cultures the fetal cells and examines the complete chromosome complement under the microscope, detecting numerical abnormalities and larger structural rearrangements across all chromosomes. Chromosomal microarray analysis offers higher resolution again, detecting submicroscopic microdeletions and microduplications that a standard karyotype cannot resolve.
Good to know
- Sample
- Amniotic fluid / chorionic villi (from invasive sampling)
- Methods
- QF-PCR, karyotype, chromosomal microarray
- Role
- Confirmatory diagnostic testing
Who is this for?
Pregnancies undergoing amniocentesis or CVS; confirmation after a high-risk screening result; clinically indicated chromosomal diagnostics
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
The laboratory is headed by RNDr. Jitka Kadlecová, Ph.D., supported by a team of cytogenetic and molecular genetic specialists with long-term laboratory experience in prenatal and postnatal genetic diagnostics.
Languages: Czech, English
Treatment highlights
- Laboratory analysis of amniotic fluid or chorionic villus sample
- Choice of QF-PCR rapid aneuploidy detection, full karyotype, or microarray
+1 more item in What's included
From 2,000 Kč for rapid chromosome 21 aneuploidy detection by QF-PCR. Aneuploidy panel for chromosomes 13, 18, 21, X and Y is 3,500 Kč. Microdeletion/microduplication analysis (microarray) is 9,500 Kč. Full karyotype from amniotic fluid or chorionic villi is 6,500 Kč. Prices cover laboratory analysis of the provided sample.