Type
Genetic Testing
Duration
15 min
Sample
Blood (venous)
What's included
5 deliverables in this treatment
- Venous blood draw
- White blood cell culture and chromosome preparation
- Microscope analysis of the full chromosome set
- Written cytogenetic report
- Optional expedited STAT turnaround
A karyotype is a microscope-level analysis of all of a person's chromosomes, prepared by culturing cells from a peripheral blood sample. It detects numerical chromosome abnormalities and larger structural rearrangements such as translocations, deletions, and duplications. The test is commonly requested in the work-up of infertility, recurrent pregnancy loss, developmental concerns, or a family history of chromosomal conditions. An expedited STAT option is available when a faster result is needed.
About this treatment
Karyotyping examines the full set of an individual's chromosomes — their number, size, and structure — under the microscope. White blood cells from a peripheral blood sample are cultured in the laboratory, arrested at the stage of cell division where chromosomes are most condensed and visible, then stained and arranged into a karyogram for analysis.
The test reliably detects numerical abnormalities (such as an extra or missing chromosome) and structural abnormalities visible at the chromosomal level, including balanced and unbalanced translocations, large deletions and duplications, inversions, and ring chromosomes. These findings are particularly relevant in the investigation of infertility and recurrent miscarriage, where a balanced chromosomal rearrangement in one partner can be the underlying…
The laboratory offers a standard turnaround as well as an expedited STAT karyotype for situations where the result is needed more quickly. Because chromosome analysis requires living cells to be cultured, a minimum processing time is unavoidable. Karyotyping complements molecular methods such as microarray, which resolves smaller submicroscopic changes that a karyotype cannot detect; the laboratory advises on the most appropriate method for the clinical…
Good to know
- Sample
- Venous blood
- Detects
- Numerical and structural chromosome abnormalities
- Turnaround
- Standard or expedited STAT
Who is this for?
Infertility and recurrent miscarriage work-up; developmental concerns; family history of chromosomal rearrangements
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
The laboratory is headed by RNDr. Jitka Kadlecová, Ph.D., supported by a team of cytogenetic and molecular genetic specialists with long-term laboratory experience in prenatal and postnatal genetic diagnostics.
Languages: Czech, English
Treatment highlights
- Venous blood draw
- White blood cell culture and chromosome preparation
+3 more items in What's included
5,000 Kč for a standard peripheral blood karyotype. 6,000 Kč for an expedited (STAT) karyotype with a faster turnaround. Price covers the blood draw, cell culture, and chromosome analysis.