

PLLA Dermal Biostimulator — Poly-L-Lactic Acid Filler
Type
Botox & Fillers
Duration
30 min
What's included
4 deliverables in this treatment
- Facial or body zone assessment and volume planning by MUDr. Moskalyková
- PLLA biostimulator injection — single or multi-session protocol
- Post-injection massage instruction for even microsphere distribution
- Three-week follow-up review to assess collagen response and plan top-up if needed
PLLA (poly-L-lactic acid) injectable biostimulators at CLED provide volumising and firming effects through a mechanism fundamentally different from hyaluronic acid fillers: rather than adding immediate volume, PLLA micro-particles stimulate the body's own fibroblasts to produce new collagen type I, creating gradual, natural-looking volume restoration with results that may last up to 24 months. MUDr. Moskalyková uses PLLA for facial contouring of temples, chin, jawline and cheeks, and for body areas including the décolletage, neck, arms and buttocks.
About this treatment
Poly-L-lactic acid (PLLA) is a biodegradable synthetic polymer originally used in dissolvable surgical sutures. In its injectable form as a dermal biostimulator, it is prepared as a suspension of microspheres reconstituted in sterile water before injection. These microspheres, once deposited in the subcutaneous tissue or deep dermis, trigger a controlled foreign-body inflammatory reaction that activates fibroblasts in the surrounding tissue. These…
This mechanism distinguishes PLLA from conventional HA fillers in several practically important ways. First, results develop gradually: there is no immediate filling visible the day of injection (the initial volume from the reconstituting fluid resorbs within a few days). The collagen production cascade takes two to three weeks to become visible, and continues to build over several weeks after injection, producing a natural-looking progression rather than…
At CLED MUDr. Moskalyková administers PLLA for the face — particularly the temples (one of the first areas to hollow with age), cheekbones, chin and jawline — and for body areas where conventional fillers would be impractical due to the volume required: décolletage lines, neck laxity, loose arm skin, buttock contouring, and upper thigh or abdominal skin quality improvement.
Good to know
- Mechanism
- Biostimulator — triggers natural collagen type I production
- Result onset
- Gradual — visible from 3 weeks post-injection
- Duration
- Up to 24 months
- Treatment areas
- Face, neck, décolletage, arms, buttocks, thighs
Who is this for?
Adults seeking long-lasting, natural-looking facial volume restoration or body contouring who prefer a gradual, biostimulating approach over instant HA filler results
Preparation required
Avoid blood-thinning medications and alcohol for 48 hours before. Inform MUDr. Moskalyková of any autoimmune conditions. Do not treat during active skin infection. Massage the treated area as instructed for five minutes five times daily for five days after treatment.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
CLED is founded and led solely by MUDr. Miloslava Moskalyková, a graduate of the 1st Faculty of Medicine of Charles University (1. LF UK). She holds first-degree board certification in dermatovenerology (1997) and second-degree board certification in corrective dermatology (2000) — a two-tier specialisation that spans both medical diagnosis and aesthetic intervention. In addition to her Czech training she completed…
Languages: Czech
Treatment highlights
- Facial or body zone assessment and volume planning by MUDr. Moskalyková
- PLLA biostimulator injection — single or multi-session protocol
+2 more items in What's included
From approximately 10,000 Kč per session (market reference for PLLA biostimulators — contact +420 606 035 141 for a consultation and personalised pricing). Effect builds gradually over 3 weeks; results may last up to 24 months. Can be repeated after 4 weeks if further volume is desired.
