Longevity.haus
MUDr. Miloslava Moskalyková — founder and lead dermatologist at CLED Prague
CLED clinic location in Uhříněves, Prague 10

Botulotoxin — Anti-Wrinkle Treatment

Type

Botox & Fillers

Duration

30 min

What's included

4 deliverables in this treatment

  • Pre-injection facial dynamics assessment and muscle mapping by MUDr. Moskalyková
  • Botulotoxin injection into agreed areas with ultra-fine needles
  • Detailed aftercare instructions covering movement, position and activity restrictions
  • Optional follow-up symmetry review at 3–4 weeks

Botulotoxin injections to relax the facial muscles driving dynamic expression lines — forehead lines, glabellar frown lines and crow's feet — administered exclusively by MUDr. Miloslava Moskalyková. She maps each patient's muscle activity before injection to place each dose at the optimal site. Effect onset is 2–21 days; first-treatment duration is typically 4–6 months, extending to 6–12 months with subsequent sessions. The clinic also uses botulotoxin for hyperhidrosis (excessive sweating) of the underarms, palms and soles.

About this treatment

Botulotoxin works at the neuromuscular junction by blocking acetylcholine release — the chemical messenger that signals a muscle to contract. When a measured dose is placed in a specific facial muscle such as the frontalis (forehead), corrugators or procerus (glabellar frown complex), or orbicularis oculi (crow's feet), that muscle's contractile activity is temporarily suspended. The overlying skin stops being mechanically creased with every expression;…

MUDr. Miloslava Moskalyková begins every session by observing the patient's natural facial dynamics — how the forehead lifts, where the brow furrows, how the eye corners crease. This functional mapping determines both injection location and dose per muscle: brow position, brow symmetry and muscle mass all influence how much product achieves the desired relaxation without over-weakening adjacent muscles. Ultra-fine needles are used throughout; the entire…

Post-treatment protocol at CLED follows established guidelines: patients are advised to stay upright for four hours, avoid strong pressure on the treated areas, skip saunas, vigorous exercise and alcohol for the first six hours, and actively contract the treated muscles in the two hours after injection to assist product distribution. If the lower eyelid is treated, artificial tears are recommended preventively.

Good to know

Effect onset
2–21 days; full result by day 21
Duration
4–6 months (first treatment); 6–12 months (repeat)
Performed by
MUDr. Miloslava Moskalyková — physician only
Also treats
Hyperhidrosis (excessive sweating)

Who is this for?

Adults seeking to soften forehead lines, glabellar frown lines or crow's feet; patients with excessive underarm, palm or plantar sweating (hyperhidrosis)

Preparation required

Avoid aspirin, ibuprofen and vitamin E supplements for 48 hours before. Do not apply moisturiser or make-up on treatment areas. Stay upright for 4 hours after treatment; avoid vigorous exercise and saunas for 6 hours.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

CLED – Centrum laserové a estetické dermatologie clinical team

Clinical team

CLED is founded and led solely by MUDr. Miloslava Moskalyková, a graduate of the 1st Faculty of Medicine of Charles University (1. LF UK). She holds first-degree board certification in dermatovenerology (1997) and second-degree board certification in corrective dermatology (2000) — a two-tier specialisation that spans both medical diagnosis and aesthetic intervention. In addition to her Czech training she completed…

Languages: Czech

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