Metabolic & Insulin Resistance Panel

An 18-biomarker panel targeting the metabolic dysfunction that underlies type 2 diabetes, cardiovascular disease, and accelerated ageing. Measures HbA1c, fasting insulin, fasting glucose, and HOMA-IR for insulin resistance quantification, alongside lipids, cortisol, DHEA-S, vitamin D, magnesium, zinc, and CRP. Designed to detect metabolic syndrome at its earliest stage — when lifestyle intervention is most effective and medication is avoidable.

Metabolic syndrome is a cluster of interconnected risk factors — insulin resistance, abdominal obesity, high triglycerides, low HDL, and elevated blood pressure — that dramatically increases cardiovascular and diabetes risk. This panel measures the biomarkers that detect each component. The glucose trio (HbA1c, fasting insulin, fasting glucose) with HOMA-IR calculation provides the most sensitive detection of insulin resistance — appearing years before fasting glucose rises. The lipid profile reveals the characteristic metabolic syndrome pattern: high triglycerides with low HDL. Morning cortisol and DHEA-S assess the stress axis, because chronic cortisol elevation drives visceral fat accumulation, insulin resistance, and metabolic dysfunction in a self-reinforcing cycle. Micronutrients are included because deficiency in magnesium, zinc, and vitamin D independently impairs insulin sensitivity. Magnesium is a cofactor in glucose metabolism — deficiency is both a cause and consequence of insulin resistance. Zinc supports insulin storage and secretion. Vitamin D receptors exist on pancreatic beta cells and influence insulin production. CRP measures the systemic inflammation that accompanies and accelerates metabolic dysfunction. This panel provides the complete picture for metabolic health optimisation.