Male Fertility & Hormone Screen

A 37-biomarker panel assessing the hormonal, nutritional, and metabolic factors that influence male fertility, sperm quality, and reproductive health. Measures total and free testosterone, SHBG, LH, FSH, DHEA-S, prolactin, and estradiol alongside thyroid function, zinc, vitamin D, B12, folate, and iron studies — the nutrients with the strongest evidence base for supporting male reproductive outcomes.

Male factor contributes to approximately 40-50% of infertility cases, yet male fertility testing often begins and ends with a semen analysis. The Male Fertility & Hormone Screen investigates the hormonal and nutritional environment that determines sperm production, quality, and function. Total and free testosterone (calculated via SHBG) assess the primary driver of spermatogenesis. LH and FSH from the pituitary gland signal the testes to produce sperm and testosterone — abnormal levels distinguish between primary testicular issues and central hormonal dysfunction. Estradiol in men affects libido, erectile function, and sperm maturation; both excess and deficiency are problematic. Prolactin elevation suppresses gonadotropins and is a treatable cause of low testosterone and subfertility. DHEA-S provides insight into adrenal androgen production. Thyroid function affects sperm morphology and motility — both hyper and hypothyroidism impair male reproductive function. The nutritional component targets the micronutrients with the strongest fertility evidence. Zinc is concentrated in seminal fluid and is essential for sperm production and testosterone synthesis. Folate supports DNA integrity in sperm. Vitamin D receptors exist on sperm cells and influence motility. B12 affects sperm count and motility. Iron studies complete the picture by assessing oxygen transport to reproductive tissues. This panel provides the data for evidence-based preconception planning, allowing men to optimise modifiable factors before attempting conception.