Gut Health & Digestion Panel

A 25-biomarker panel investigating the inflammatory, immune, and nutritional markers that drive digestive dysfunction. Measures CRP, ESR, immunoglobulins (IgA, IgG, IgM), zonulin (intestinal permeability), calprotectin (gut-specific inflammation), vitamin D, B12, folate, and a full blood count. Designed for anyone with chronic bloating, IBS symptoms, food sensitivities, or poor nutrient absorption despite adequate dietary intake.

Chronic digestive symptoms — bloating, irregular bowel habits, food sensitivities, abdominal pain, and poor nutrient absorption — affect a significant proportion of the population, yet standard medical tests often return normal results. This 25-biomarker panel investigates the inflammatory, immune, and nutritional markers that drive digestive dysfunction, looking for the causes that standard tests miss. The panel includes CRP and ESR for systemic inflammation, which can be elevated in inflammatory bowel disease and other gut-related conditions. Immunoglobulins (IgA, IgG, IgM) assess the immune system's mucosal defence — IgA is particularly relevant as it is the primary antibody in the gut lining. Zonulin measures intestinal permeability (so-called leaky gut), a condition where the tight junctions between intestinal cells become compromised, allowing partially digested food proteins and bacterial toxins to enter the bloodstream. Calprotectin is a gut-specific inflammation marker that distinguishes inflammatory bowel disease (Crohn's, ulcerative colitis) from irritable bowel syndrome — a distinction that is difficult to make on symptoms alone. Vitamin D, B12, and folate are included because poor absorption is both a consequence of gut dysfunction and a contributor to impaired gut healing. A full blood count screens for anaemia and immune cell abnormalities. An 8-12 hour fast with a morning blood draw is recommended. ClearLabs delivers results within 2-3 business days through the digital dashboard. This panel is particularly valuable for people with IBS symptoms who want to rule out or identify an inflammatory component, those with suspected food sensitivities, and anyone experiencing poor nutrient absorption despite adequate dietary intake.