DUTCH Hormone Panel

An advanced dried urine test measuring sex hormones and adrenal hormones with their metabolites — providing deeper insight than standard blood tests into how your body produces, processes, and eliminates hormones. The DUTCH (Dried Urine Test for Comprehensive Hormones) method captures hormone metabolites that blood testing misses, revealing methylation pathways, cortisol patterns, and oestrogen metabolism routes associated with cancer risk.

Standard blood hormone tests measure total hormone levels at a single point in time. The DUTCH panel goes further by measuring hormone metabolites in dried urine — revealing not just how much hormone is present but how your body processes and eliminates it. For cortisol, the DUTCH method captures the total daily cortisol output and its metabolites, providing a more complete picture of adrenal function than a single morning blood draw. This reveals patterns invisible to blood testing — such as high free cortisol with normal total cortisol (suggesting impaired cortisol metabolism) or normal morning cortisol that crashes abnormally fast. For oestrogen, metabolite ratios (2-OH, 4-OH, 16-OH pathways) indicate whether oestrogen is being processed through protective or potentially harmful pathways — the 4-OH pathway is associated with DNA damage and increased cancer risk. This information guides targeted interventions (DIM, cruciferous vegetables, methylation support). The test involves collecting small dried urine samples on filter paper at specific times over 24 hours — done at home, no collection centre visit needed for the urine component. Results are delivered through ClearLabs' dashboard with detailed metabolite breakdowns.