Brain & Cognitive Function Panel

A 31-biomarker panel investigating the nutritional, inflammatory, hormonal, and metabolic factors that influence cognitive performance, memory, and long-term brain health. Covers vitamin B12, folate, vitamin D, homocysteine, iron studies, full thyroid panel, hs-CRP, full blood count, and liver markers — with optional APOE genotyping for Alzheimer's risk assessment. Built for anyone experiencing brain fog, memory concerns, or proactively protecting cognitive function.

Cognitive decline is not an inevitable consequence of ageing — it is driven by modifiable biological factors that blood testing can identify and track. This panel systematically screens the domains most strongly linked to brain health. Homocysteine is an independent risk factor for cognitive decline, dementia, and stroke. Elevated levels indicate impaired methylation — the biochemical process that maintains DNA, produces neurotransmitters, and repairs myelin. B12, folate, and B6 are the cofactors that keep homocysteine in check, and deficiency in any one drives levels up. Thyroid hormones directly affect cognitive speed, memory consolidation, and mood. Subclinical hypothyroidism — common and easily missed — causes reversible cognitive impairment that mimics early dementia. Iron deficiency reduces oxygen delivery to the brain, impairing concentration and memory before haemoglobin drops enough to trigger an anaemia diagnosis. Chronic neuroinflammation (measured via hs-CRP) is increasingly recognised as a driver of neurodegeneration. Vitamin D receptors are concentrated in brain regions involved in memory and mood, and deficiency is associated with accelerated cognitive decline in longitudinal studies. The optional APOE genotype identifies carriers of the APOE4 allele — the strongest genetic risk factor for late-onset Alzheimer's disease. While not diagnostic, this information enables earlier and more aggressive preventive strategies for carriers.