GUNA Joint Injections

GUNA injections at Bolest Brno deliver a natural preparation combining hyaluronic acid with plant-based extracts developed by the Italian GUNA biologics company. Injections are administered at targeted musculoskeletal sites — typically around painful joints or soft-tissue trigger points — by the clinic's interventional algesiologists, not by nursing staff. A standard course runs to 10 applications given once a week over 10 weeks, for a total of 3 000 Kč. The hyaluronic acid component helps restore joint lubrication and reduce friction, while the plant extract matrix is intended to provide additional local anti-inflammatory support. The treatment is suited to joint pain and osteoarthritis-related conditions where patients prefer a non-synthetic or minimally pharmaceutical approach, and is used alongside other pain management modalities at the clinic.

GUNA is an Italian company specialising in biological medicinal preparations. Their injectable products combine high-molecular-weight hyaluronic acid — the same substance produced naturally in synovial joint fluid — with a proprietary blend of homeopathic plant extracts. The combination is designed to restore lubrication, reduce mechanical friction within the joint and modulate the local inflammatory environment through the plant extract component. At Bolest Brno, GUNA injections are performed by the clinic's interventional algesiologists, who determine the precise injection site through clinical assessment of each patient. The injection is applied to the most painful or dysfunctional area — typically a joint capsule, periarticular soft tissue, or trigger point — under aseptic technique. The session itself takes around 20–30 minutes including a brief pre-injection assessment and post-injection observation. **Course structure:** The standard protocol is 10 applications, each given once weekly over 10 consecutive weeks. This schedule allows gradual accumulation of hyaluronic acid within joint tissues and progressive symptom reduction. Some patients notice improvement by sessions 3–4; others require the full 10-session course for optimal effect. The clinic will review progress at session 5 and adjust the plan if needed. **Conditions addressed:** Joint pain due to mild-to-moderate osteoarthritis (knee, hip, shoulder, small joints of the hand and foot), periarticular pain, myofascial pain, conditions where standard corticosteroid injections are not indicated or not preferred by the patient, and adjunct to physiotherapy or acupuncture programmes. **Comparison with standard hyaluronic acid injections:** GUNA preparations differ from pharmaceutical-grade viscosupplementation products (e.g. Synvisc, Hyalgan) in that they include homeopathic plant extracts. They are classified as natural preparations rather than pharmaceutical medical devices and are not subject to the same clinical evidence requirements. Patients who prefer a non-synthetic approach or who cannot use standard anti-inflammatory drugs may find them a useful addition to a multimodal pain programme. **Integration with other treatments:** At Bolest Brno, GUNA injections are often used alongside acupuncture, nerve blocks or pharmacotherapy as part of an individualised pain management plan designed by the treating algesiologist. **Preparation and aftercare:** No specific fasting or preparation is required. Avoid strenuous physical activity or heat application to the injected area for 24 hours after each session. If significant local swelling or warmth occurs, contact the clinic. Anti-inflammatory medications are generally not needed after GUNA injections unless specifically prescribed. **Contraindications:** Active local infection, known allergy to hyaluronic acid or any GUNA preparation component, active malignancy at the injection site, haemophilia or active anticoagulant therapy at therapeutic levels. Relative: pregnancy, severe systemic illness.