Type
Blood Testing
Biomarkers
7
Duration
15 min
A comprehensive thyroid panel measuring TSH, free T4, free T3, reverse T3, and thyroid antibodies (anti-TPO, anti-TG) to provide a complete picture of thyroid function, conversion efficiency, and autoimmune thyroid status. Substantially more thorough than the single TSH marker typically ordered by GPs.
Standard thyroid screening in the Netherlands typically begins and ends with TSH — a pituitary hormone that provides only an indirect signal about thyroid output. While TSH is a useful first-line marker, it can miss subclinical thyroid dysfunction, conversion problems between T4 and T3, and early autoimmune thyroid disease. The Schildklier Totaal panel addresses these gaps by measuring the full thyroid axis. Free T4 (the primary thyroid hormone) and free T3 (the biologically active form) reveal whether the thyroid is producing adequate hormone and whether T4 is being efficiently converted to T3 in peripheral tissues. Reverse T3 is a metabolically inactive form of T3 that can accumulate during illness, chronic stress, or caloric restriction — its measurement helps distinguish true hypothyroidism from non-thyroidal illness syndrome. Anti-TPO and anti-TG antibodies screen for Hashimoto's thyroiditis and other autoimmune thyroid conditions, which can be present for years before TSH moves outside the reference range. At EUR 259, this panel provides the kind of thorough thyroid assessment that would typically require a specialist endocrinology referral through the Dutch healthcare system. It is particularly relevant for individuals with persistent fatigue, unexplained weight changes, cold intolerance, hair thinning, or mood changes who have been told their TSH is normal, as well as those with a family history of thyroid disease or existing thyroid conditions who want to monitor their full thyroid function.
Key Details
- Biomarkers
- 7
- Focus
- Complete thyroid axis
- Includes
- Antibodies + reverse T3
- GP referral
- Not required
Who Is This For?
Thyroid symptom investigation, normal-TSH fatigue, family history of thyroid disease, autoimmune thyroid screening, monitoring existing thyroid conditions
What's Included
- Category
- Diagnostic
- Duration
- 15 min
