PRP / PRF Plasma Therapy

Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) therapy at BESTÉE Clinic harnesses the patient's own growth factors to stimulate tissue regeneration and collagen production. A small blood draw is centrifuged to concentrate platelets, which release a cascade of growth factors (PDGF, TGF-β, VEGF, IGF-1) when activated at the treatment site. At BESTÉE Clinic, plasma therapy is applied both to the face (via microinjections for skin rejuvenation) and to the scalp (for androgenetic, postpartum, and menopausal alopecia). The autologous nature of the treatment eliminates allergy risk and aligns with the clinic's broader focus on biostimulatory approaches to aesthetics.

PRP and PRF therapy at BESTÉE Clinic extracts and concentrates the patient's own platelet-derived growth factors, then delivers them precisely to target tissue to trigger regeneration. The procedure is entirely autologous — derived from the patient's own blood — eliminating the risk of allergic reaction or rejection. The preparation process begins with a venous blood draw of 10–30ml. The blood is placed into a centrifuge and spun at a calibrated speed and duration to separate the plasma fraction enriched in platelets from the red blood cell and platelet-poor plasma layers. The resulting PRP has a platelet concentration 3–8x higher than baseline whole blood. PRF preparation uses a slightly different protocol — no anticoagulant, slower spin — producing a fibrin matrix that releases growth factors more slowly and sustainably over 7–14 days. When activated at the injection site (by calcium chloride for PRF, or upon contact with tissue collagen for PRP), the alpha granules within platelets release a concentrated payload of growth factors including platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-β), vascular endothelial growth factor (VEGF), and insulin-like growth factor 1 (IGF-1). These signals stimulate fibroblast proliferation, new collagen and elastin deposition, angiogenesis, and local cell recruitment. At BESTÉE Clinic, the primary applications are: **Scalp — hair loss:** Plasma injections into the scalp dermis stimulate resting hair follicles (telogen phase) to re-enter the active growth phase (anagen), increase follicle diameter, and slow or reverse miniaturisation. The clinic treats androgenetic alopecia, postpartum hair loss, menopausal alopecia, and diffuse hair thinning, pricing scalp PRP protocols from 7,000 Kč per session. A course of 3–6 sessions at monthly intervals is standard, with annual maintenance sessions thereafter. **Face — skin rejuvenation:** Facial PRP is delivered via intradermal microinjections across the entire face or targeted zones (under-eyes, forehead, cheeks), improving skin tone, texture, fine lines, and elasticity through direct fibroblast stimulation. Because the treatment uses the patient's own blood, contraindications are minimal: active infection at the treatment site, platelet disorders, anticoagulant medications, and active cancer represent the primary exclusions. No downtime is required, though temporary redness and pinpoint bruising resolve within 24–48 hours.