Erschöpfungs Check-Up

A fifteen-biomarker panel targeting the most common blood-level causes of persistent fatigue: iron status, thyroid function, blood sugar regulation, vitamin deficiencies, and inflammatory markers. Designed as a systematic first-line investigation for individuals experiencing unexplained tiredness, low energy, or reduced physical and mental performance.

Persistent fatigue is one of the most common complaints in primary care, yet its causes are diverse and frequently overlooked in standard consultations. This panel is structured to systematically screen the biological factors most commonly responsible: iron deficiency (the leading cause of fatigue in premenopausal women), thyroid dysfunction, blood sugar dysregulation, vitamin deficiencies, and chronic low-grade inflammation. The haematological component identifies anaemia and characterises its type — iron-deficiency anaemia presents differently from B12 or folate deficiency anaemia, and the treatment differs accordingly. Ferritin levels can be suboptimal and drive fatigue well before full anaemia develops, which is why iron stores are measured alongside the complete blood count. Thyroid markers screen for both hypothyroidism (the classic fatigue-causing thyroid disorder) and subclinical thyroid dysfunction. Vitamin D, B12, and folate are measured because deficiencies in each are common in the central European population and directly affect energy production, neurological function, and mood. Inflammatory markers help identify whether chronic inflammation — from infection, autoimmune activity, or other sources — may be contributing to the fatigue picture. This panel is designed to either identify a clear cause or rule out the most likely biological contributors, providing a rational basis for next steps.