NAD+ Infusion 500mg

A high-dose 2-hour intravenous NAD+ infusion delivering 500mg for intensive cellular replenishment, suited for initial loading protocols, age-related NAD+ depletion, or clients seeking maximum therapeutic effect.

The 500mg NAD+ infusion at Ayvie Health is the higher-dose option, delivering 2.5 times the coenzyme load of the standard 200mg session. This dosage is typically recommended for initial loading protocols (clients new to NAD+ therapy who want to rapidly restore depleted levels), individuals over 50 with more significant age-related NAD+ decline, or those seeking the maximum therapeutic effect from each session. The pharmacological rationale for the higher dose is straightforward: at 500mg, more NAD+ reaches the cells and more substrate is available for the NAD+-dependent enzymes (sirtuins, PARPs, CD38) that drive DNA repair, mitochondrial function, and epigenetic regulation. Some longevity protocols recommend an initial series of 3 to 5 high-dose sessions followed by monthly maintenance at the lower 200mg dose. The infusion time remains approximately 2 hours despite the higher dose, as the drip rate is carefully managed to minimise the temporary side effects that can occur when NAD+ enters the bloodstream too quickly. The medical team at Ayvie monitors vitals and adjusts the rate based on individual tolerance. Clients who have previously tolerated the 200mg dose well typically find the 500mg session similarly comfortable. Ayvie operates a dedicated NAD+ programme through its nadplusberlin.de subdomain, reflecting the growing demand for this specific therapy in Berlin's wellness-conscious population. All NAD+ used is pharmaceutical-grade, and the infusion is administered in a comfortable lounge-style setting designed for the extended treatment duration.