NAD+ Infusion 200mg

A 2-hour intravenous NAD+ infusion delivering 200mg of nicotinamide adenine dinucleotide directly into the bloodstream, bypassing digestive absorption to support cellular energy production, DNA repair, and mitochondrial function.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, essential for hundreds of metabolic processes including energy production in the mitochondria, DNA repair, sirtuin activation (associated with longevity pathways), and neurotransmitter synthesis. NAD+ levels decline naturally with age — by age 50, levels may be half of what they were at age 20 — contributing to cellular dysfunction, reduced energy, and accelerated ageing processes. Intravenous NAD+ therapy delivers the coenzyme directly into the bloodstream at concentrations that cannot be achieved through oral supplementation, which loses 80-90% of its bioavailability to first-pass metabolism in the gut and liver. The 200mg dose at Ayvie Health is positioned as the standard therapeutic dose suitable for regular maintenance, anti-ageing support, and energy optimisation. The infusion takes approximately 2 hours due to the need for a slow drip rate — NAD+ delivered too quickly can cause temporary side effects including flushing, nausea, and chest tightness. Ayvie's medical team monitors the infusion rate and adjusts based on the client's tolerance. Most clients report feeling more energised and mentally clear within hours of the infusion, with peak effects developing over the following 1 to 3 days. NAD+ therapy has gained significant attention in the longevity and biohacking community following research by David Sinclair and others linking NAD+ levels to ageing biomarkers. While clinical evidence in humans is still developing, preclinical and early clinical data support potential benefits for energy metabolism, cognitive function, neuroprotection, and cellular resilience to stress.