Thyroid Hormone Panel

A thyroid hormone panel starting from the TSH + fT4 screening pair (349 Kč) at AXIS-CZ's NASKL-accredited laboratory in Hradec Králové. TSH (thyroid-stimulating hormone) is the primary screening marker for thyroid dysfunction; fT4 (free thyroxine) is the main circulating thyroid hormone and the key diagnostic pair alongside TSH. AXIS-CZ runs a seasonal World Thyroid Day promotion offering these two markers at 349 Kč — reduced from the combined individual price of around 505 Kč. The extended panel of eight individual markers covers fT3, total T3, total T4, Anti-TPO, Anti-TG, TRAK, and thyroglobulin for comprehensive autoimmune and functional assessment. No fasting is required. Collection runs from 05:30 Monday to Friday without an appointment, and results are typically available the same or next working day.

The thyroid panel at Laboratoř AXIS-CZ provides a tiered approach to thyroid assessment, from a basic two-marker screening pair through to a comprehensive autoimmune and functional panel covering all eight clinically relevant thyroid markers. The TSH + fT4 screening pair is the internationally recommended first-line investigation for thyroid dysfunction. TSH (thyrotropin), secreted by the anterior pituitary, is the most sensitive indicator of thyroid status: it rises in hypothyroidism (the pituitary works harder to stimulate an underperforming thyroid) and falls in hyperthyroidism (the pituitary reduces stimulation in response to excess thyroid hormone). fT4 — free thyroxine, the biologically available fraction of the main thyroid hormone — confirms and characterises the functional state: in primary hypothyroidism both TSH is high and fT4 is low; in subclinical hypothyroidism TSH is elevated but fT4 remains normal; in hyperthyroidism TSH is suppressed and fT4 is elevated. For patients where autoimmune thyroid disease is suspected — particularly Hashimoto's thyroiditis (the most common cause of hypothyroidism in adults, and frequently the cause of unexplained fatigue and weight change in women) or Graves' disease (autoimmune hyperthyroidism) — the extended markers are highly valuable. Anti-TPO (thyroid peroxidase antibodies) are positive in around 90% of Hashimoto's cases and around 75% of Graves' cases. Anti-TG (thyroglobulin antibodies) are a secondary autoimmune marker, less specific on their own but informative alongside Anti-TPO. TRAK (TSH receptor antibodies) are the specific marker for Graves' disease and are used both for diagnosis and for monitoring response to antithyroid treatment or assessing risk of neonatal hyperthyroidism in pregnancy. fT3 (free triiodothyronine) — the biologically active form of thyroid hormone — is measured when T3-dominant hyperthyroidism is suspected (TSH suppressed, fT4 normal but fT3 elevated) or in monitoring patients on T3-containing thyroid hormone replacement therapy. Thyroglobulin is measured as a tumour marker in patients who have had thyroid cancer and thyroidectomy, where it serves as the primary monitoring biomarker for recurrence. No fasting is required for any thyroid marker. Collection is available from 05:30 Monday to Friday without an appointment. Results are available the same day for TSH and fT4; autoimmune markers may take one additional working day. The blood draw fee of 59 Kč for adults is charged additionally. AXIS-CZ's published price list allows patients to order exactly the markers their clinician recommends rather than a fixed panel, making it cost-effective for both simple screening and comprehensive thyroid assessment.