Tissue Stimulators (Profhilo, Nucleofill & more)

Injectable tissue stimulators and bio-remodelling products that improve the skin's firmness, hydration and quality rather than adding shape or volume. Delivered to precise points, products such as Profhilo, Nucleofill, Ejal40 and Jalupro disperse through the skin and prompt its own support structures, helping address laxity, texture and glow. They suit patients who want healthier-looking skin and are a popular step for those new to injectables.

Tissue stimulators are injectable treatments that work by encouraging the skin to improve its own structure and hydration over the weeks after treatment, rather than filling a line or adding contour. AWitczak Clinic offers a range of established products — including Profhilo and Karisma for bio-remodelling, Nucleofill, the amino-acid based Jalupro Super Hydro and the hydrating Ejal40 — each suited to slightly different concerns around skin laxity, dehydration and overall quality. The physician recommends the most appropriate product and protocol at consultation. Most of these treatments are delivered to a small number of strategic points and take around fifteen to twenty minutes. Because only a few injection points are used, downtime is usually minimal: small raised bumps settle within hours and any pinpoint marks fade quickly. Several products, such as Profhilo, follow a standard protocol of two sessions roughly four weeks apart, with results building over the following one to two months and commonly maintained with a session every six months or so. They are typically used on the lower face and are also suited to the neck, décolleté and the backs of the hands. Tissue stimulators are a good option for adults whose main concern is dull, lax or dehydrated skin rather than volume loss or deep folds, and they combine well with toxin and filler as part of a wider plan. Suitability and any contraindications are reviewed beforehand.