High-Dose IV Vitamin C Infusion

Aura Medical Clinic administers pH-neutral, preservative-free intravenous vitamin C at therapeutic doses ranging from 7.5 grams for antioxidant and immune support up to 15–50 grams for oncological adjunct protocols — concentrations only achievable via IV, far beyond oral absorption limits. The treatment is registered with SÚKL (the Czech State Institute for Drug Control) and requires a physician prescription. At higher doses, vitamin C acts as a pro-oxidant in tumour microenvironments by generating hydrogen peroxide selectively within malignant cells, while maintaining its antioxidant role in healthy tissue. MUDr. Hajduk has incorporated this protocol into the clinic's integrative medicine offer, and the clinic's published clinical rationale cites US National Cancer Institute research labelling the approach 'non-toxic chemotherapy' as a supportive modality.

High-dose intravenous vitamin C has been part of Aura Medical Clinic's integrative medicine protocol since the early years of the clinic's operation, administered under a physician prescription and SÚKL registration as a regulated medicinal preparation. The preparation used is pH-neutral and entirely free of preservatives, ensuring tolerability even at high doses in medically sensitive patients. **The science of IV vitamin C.** Oral vitamin C has a bioavailability ceiling of roughly 200–400 mg per dose before intestinal absorption saturates — regardless of how much is ingested. Intravenous administration bypasses this entirely, allowing plasma concentrations 30–70 times higher than oral megadosing can achieve. At these supraphysiological concentrations, vitamin C exhibits two distinct mechanisms: an **antioxidant effect** in normal tissue (scavenging free radicals, supporting immune cell function, and protecting against oxidative damage) and a **pro-oxidant effect** in tumour microenvironments, where it generates hydrogen peroxide (H2O2) through a Fenton-like reaction, selectively toxic to cells with depleted catalase activity — a hallmark of many malignant cells. This dual mechanism is the basis for its use as an oncology supportive therapy, endorsed by the US National Cancer Institute for further study. **Protocols at Aura Medical Clinic.** Three dosing tiers are used depending on indication: - **Antioxidant / prevention protocol:** 7.5 g per infusion, administered over approximately 60 minutes. Indicated for autumn immune support, post-infection recovery, recurrent infections, fatigue, and general oxidative stress. - **Therapeutic protocol:** 15–25 g, administered over 90–120 minutes. Used for severe or chronic infections, autoimmune support, arthritis, and atherosclerosis. - **Oncological support protocol:** 25–50 g at 0.1–1.0 g/kg body weight, administered over 2–3 hours, typically 2–3 times per week. Used as adjunct to conventional oncology treatment, not as a replacement. Requires referral from an oncologist or GP. **Clinical applications.** Beyond oncology adjunct use, the clinic applies IV vitamin C for recurrent infections and allergies, inflammatory arthritis, atherosclerosis and cardiovascular risk reduction, nervous system support, seasonal prevention programmes, and post-surgical or post-illness recovery. The broad antioxidant effect may also support skin collagen synthesis and reduce signs of premature ageing. **Session structure.** An initial physician consultation is mandatory to assess contra-indications (including glucose-6-phosphate dehydrogenase deficiency, renal impairment, and haemochromatosis, all of which preclude high-dose administration) and determine the appropriate dosing tier. Infusions run via a peripheral IV line at a controlled drip rate. Patients rest comfortably during the infusion; light reading or work is possible. Most patients notice improved energy and reduced fatigue within 24–48 hours of the first session. **Safety profile.** At therapeutic doses under physician supervision, IV vitamin C has an excellent safety record in published trials. The SÚKL registration of the preparation used at Aura ensures pharmaceutical-grade quality control. Mild side effects (vein irritation, temporary thirst) are managed by adjusting the infusion rate.