EPN Electroporation Microneedling

Skin-renewal treatment combining micro-needling with electroporation (EPN) using the Perfection EPN device — a 9-needle pen penetrating to 0–2 mm depth with simultaneous electrical pulses that open transient pores in cell membranes, dramatically increasing absorption of active ingredients applied to the skin surface. This dual mechanism — physical micro-channels and electroporation-enhanced uptake — may support remodelling of scars and stretch marks, improvement of skin texture and hyperpigmentation, reduction of fine lines, and stimulation of hair follicles for alopecia management. The full-face session takes approximately 30–45 minutes; series of 3 are recommended.

Electroporation microneedling at Arendarska Care uses the Perfection EPN device manufactured by EunSung. The device inserts 9 ultra-fine needles (0.2 mm diameter) to a depth adjustable between 0 and 2 mm, while simultaneously emitting electrical pulses at each needle penetration point. These pulses create a transient increase in cell membrane permeability — a phenomenon known as electroporation — which allows large-molecule actives (such as hyaluronic acid, peptides, vitamins, or PRP) applied to the skin surface to pass into the dermis at concentrations that topical application alone cannot achieve. This dual mechanism distinguishes EPN from standard microneedling (which creates channels only) and from mesotherapy (which delivers product via injection rather than transcutaneous transfer). At Arendarska Care, the EPN treatment is applied to the following concerns: - **Scarring and stretch marks:** Needle channels disrupt fibrous scar tissue; electroporation enhances delivery of healing actives. From 2,000 Kč per session for a selected area. - **Hyperpigmentation:** Coordinated with brightening active ingredients delivered into the dermis. Typically face treatment at 3,000 Kč. - **Fine lines and skin texture:** Collagen-stimulating serums driven through electroporation deliver faster and deeper than topical alone. - **Hair loss therapy:** Scalp application stimulates follicle zone with micro-injury + active uptake; from 3,000 Kč/session. - **Palms:** 3,000 Kč per session for hand rejuvenation and treatment of hyperpigmentation. Sessions begin with skin cleansing and topical anaesthetic application. The practitioner then works methodically across the treatment zone with the EPN handpiece, applying the chosen active substance before or during needle passes so that electroporation channels carry it into the dermis. Redness is typical for 12–24 hours; peeling and skin tightening can occur over the following 3–5 days as renewal begins. A series of 3 sessions at 3–4 week intervals provides the deepest benefit. Series pricing at the face level (7,200 Kč for 3) offers a 20% saving vs three singles.