Tissue Biostimulators — Profhilo, Gouri, Sunekos

Skin biostimulator injections using premium tissue-stimulating preparations that work by triggering the body's own collagen and elastin synthesis rather than adding bulk volume. The clinic offers a carefully curated range including Profhilo (ultra-pure hyaluronic acid), Gouri (PCL collagen stimulator), Sunekos (amino acid + HA synergy), Jalupro, Xela Rederm, and Skinbooster Dorothy. These treatments are suited to overall skin quality improvement, fine-line softening, crepey skin on the neck and décolleté, and prevention of early skin ageing. Results develop progressively over 4–6 weeks as collagen fibres rebuild.

Tissue biostimulator injections occupy a distinct category between light mesotherapy and volume-adding fillers. Rather than filling a hollow or targeting a specific wrinkle, they diffuse through the dermis and subcutaneous tissue to stimulate fibroblasts — the cells responsible for producing collagen, elastin, and hyaluronic acid. The result is a gradual improvement in skin tone, thickness, and hydration that can appear more natural and age-appropriate than immediate-volumising approaches. Arendarska Care maintains one of the more complete biostimulator formularies among Liberec aesthetic clinics: **Profhilo (5,500 Kč / 2ml)** — Perhaps the best-known global biostimulator, using ultra-pure hybrid cooperative HA at very high concentration. Administered via 5 BAP (bio-aesthetic points) per side of the face. Two sessions 4 weeks apart is the standard protocol. It remodels lax, crepey skin without adding volume — ideal for the face, neck, décolleté, and hands. **Gouri (7,000 Kč / 1ml)** — A polycaprolactone (PCL) collagen stimulator in a liquid formulation. PCL is a longer-lasting material than PLLA; results typically develop over 3–6 months and may persist 18–24 months. Particularly effective for diffuse facial skin quality improvement. **Sunekos 200 and Performa (4,500–5,000 Kč)** — A patented combination of low-molecular-weight hyaluronic acid and a specific amino-acid formula (patented ECM-stimulating ratio) that may support the extracellular matrix regeneration. Sunekos Performa at 5,000 Kč / 3.5ml is the more intensive formulation suited to moderate skin ageing. **Xela Rederm (4,200–5,100 Kč)** — A resorbable cross-linked HA biostimulator available in three concentrations (1.1%, 1.8%, 2.2%) allowing the practitioner to titrate intensity to the skin concern. **Jalupro Classic and H&M (3,800–4,000 Kč)** — Amino-acid mesotherapy preparations containing precursors to collagen (L-proline, L-lysine, glycine, L-leucine) to support fibroblast activity. Jalupro H&M adds high molecular weight HA for added skin hydration. All biostimulator sessions at this clinic follow a standard protocol: consultation, topical anaesthetic where indicated, injections by medical doctor, post-treatment cooling and instructions. Results become visible 4–8 weeks after the first session; a standard programme of 2–4 sessions is advised.