DUTCH Hormone Testing

Comprehensive DUTCH (Dried Urine Test for Comprehensive Hormones) testing measuring estrogen, progesterone, testosterone, DHEA-S, cortisol, and their metabolites from dried urine samples collected at home. Results provide a detailed hormonal map informing bioidentical hormone replacement therapy decisions. Angel Longevity's A4M-certified Dr. Anju Mathur MD interprets results in the context of symptoms and functional medicine assessment.

DUTCH Hormone Testing at Angel Longevity Medical Center uses the Dried Urine Test for Comprehensive Hormones platform from Precision Analytical, which measures a broad array of sex hormones, adrenal hormones, and their downstream metabolites from dried urine samples collected across a single day or throughout the month depending on the protocol ordered. Unlike serum hormone panels that capture a single static snapshot at the time of blood draw, the DUTCH test's urine-based method reflects integrated hormone production and, critically, measures metabolite levels — the downstream compounds produced as the liver processes parent hormones. This metabolite mapping provides information that serum testing cannot: for example, the ratio of 2-OH estrogens to 16-OH estrogens in the estrogen metabolism pathway is not visible in blood panels but is captured in the DUTCH output, informing clinical decisions about oestrogen dominance patterns and methylation-related hormone clearance. The DUTCH Complete panel measures: the three oestrogens (estrone E1, estradiol E2, estriol E3), progesterone and its metabolites (PdG, b-pregnanediol), testosterone and its metabolites (androsterone, etiocholanolone), DHEA-S and DHEA metabolites, and the diurnal cortisol pattern across four collection points (waking, morning, afternoon, and evening) plus CAR (Cortisol Awakening Response). Dr. Anju Mathur MD, who is A4M board-certified in Anti-Aging and Regenerative Medicine and reports a 90% success rate with bioidentical hormone therapy protocols, interprets the DUTCH results within the broader context of the patient's symptoms, medical history, and functional medicine assessment to guide BHRT recommendations. The test kit is taken home; the patient performs the collection and mails dried strips back to the lab.