Rejuran & Polynucleotide Skin Boosters (Salmon DNA)

Polynucleotide (PN) skin regeneration at AMEM Zlín — headlined by Rejuran, the Korean salmon-DNA injectable that repairs skin at the cellular level rather than filling it. Purified DNA fragments stimulate fibroblast activity, dermal repair and elasticity, improving texture, fine lines, enlarged pores and post-acne skin quality over a course of treatments. The physician applies Rejuran across the full face (9,880 Kč, three-course package 23,985 Kč) or with an atraumatic needle for delicate zones. More affordable injector-applied skin boosters combining salmon DNA polynucleotides with hyaluronic acid — applied by the clinic's trained nurses — extend the menu to face, neck and décolleté from 6,900 Kč.

Polynucleotide injectables are one of the strongest trends in regenerative aesthetic medicine — and Rejuran is the product that defined the category in Korea, where it is a staple of 'glass skin' protocols. **How polynucleotides work:** PN/PDRN are purified DNA fragments derived from salmon (highly biocompatible with human tissue). Injected into the dermis, they act as biological signalling molecules: stimulating fibroblast proliferation, supporting wound-healing pathways, improving microcirculation and calming inflammation. Over a course of treatments the skin becomes measurably thicker, more elastic and more even — the improvement is regenerative, not volumising, so results look entirely natural. **What it helps:** thin, fragile or crepey skin; fine static lines; enlarged pores and rough texture; dull post-acne skin and shallow scarring; the delicate under-eye area (atraumatic needle option, from 6,940 Kč); skin weakened by sun damage. **Protocols at AMEM:** *Rejuran face (9,880 Kč)* — physician-applied micro-injections across the full face. The standard course is 3 sessions spaced 3–4 weeks apart (package 23,985 Kč, saving versus single sessions), with skin quality building progressively over the course and beyond. *Injector PN skin boosters (from 6,900 Kč)* — salmon DNA polynucleotides combined with hyaluronic acid, applied with a mesotherapy injector by the clinic's specialised nurses; available for face or extended to neck and décolleté (8,990 Kč). A gentler entry point that pairs regeneration with immediate hydration. *Crosslinked HA skin boosters (2 ml, 6,900 Kč; 2×2 ml package 11,900 Kč; 2.7 ml dense formulation for neck/décolleté 8,990 Kč)* — lightly crosslinked 20% hyaluronic acid delivering durable deep hydration to face, neck and décolleté. **The session:** cleansing, topical numbing, micro-injections or injector passes over the area (30–45 minutes). Expect small papules and possible redness for 24–72 hours as the product integrates. **Contraindications:** fish/salmon allergy (for PN products), pregnancy and breastfeeding, active skin infection, autoimmune skin disease in flare.