Type
Mesotherapy
Duration
45 min
What's included
5 deliverables in this treatment
- Skin assessment and protocol selection
- Topical numbing and cleansing
- Physician-applied Rejuran or nurse-applied injector skin booster
- Coverage options: face, under-eye, neck and décolleté
- Course planning — standard Rejuran protocol is 3 sessions 3–4 weeks apart
Polynucleotide (PN) skin regeneration at AMEM Zlín — headlined by Rejuran, the Korean salmon-DNA injectable that repairs skin at the cellular level rather than filling it. Purified DNA fragments stimulate fibroblast activity, dermal repair and elasticity, improving texture, fine lines, enlarged pores and post-acne skin quality over a course of treatments. The physician applies Rejuran across the full face (9,880 Kč, three-course package 23,985 Kč) or with an atraumatic needle for delicate zones. More affordable injector-applied skin boosters combining salmon DNA polynucleotides with hyaluronic acid — applied by the clinic's trained nurses — extend the menu to face, neck and décolleté from 6,900 Kč.
About this treatment
Polynucleotide injectables are one of the strongest trends in regenerative aesthetic medicine — and Rejuran is the product that defined the category in Korea, where it is a staple of 'glass skin' protocols.
How polynucleotides work
PN/PDRN are purified DNA fragments derived from salmon (highly biocompatible with human tissue). Injected into the dermis, they act as biological signalling molecules: stimulating fibroblast proliferation, supporting wound-healing pathways, improving microcirculation and calming inflammation. Over a course of treatments the skin becomes measurably thicker, more elastic and more even — the improvement is regenerative, not volumising, so results look…
Good to know
- Hero product
- Rejuran — salmon DNA polynucleotides (PN)
- Mechanism
- Cellular regeneration — fibroblast stimulation, not volume
- Course
- 3 sessions; package 23,985 Kč
- Downtime
- Micro-papules/redness 1–3 days
- Also available
- PN+HA and crosslinked HA boosters for neck/décolleté
Who is this for?
Skin quality repair, fine lines and crepiness, enlarged pores, post-acne texture, under-eye skin, neck and décolleté rejuvenation
Preparation required
Tell the clinic about any fish allergy — salmon-derived products are contraindicated. Avoid alcohol and blood thinners 24–48 hours before. Arrive without makeup. Small papules at injection points are normal and settle within days; avoid makeup, sauna and sport for 24 hours after.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
52 clinic reviews
From independent platforms
Clinical team
Plastic surgeon MUDr. Hana Skeřilová leads the surgical programme at the Zlín branch — she has worked in plastic surgery since 1995 (FNsP Ostrava-Poruba), headed the laser centre of the Institute of Medical Cosmetics in Ostrava from 2000, practised as an aesthetic plastic surgeon at well-known clinics in Prague and Brno, and is a member of the aesthetic surgery society. The corrective dermatology team includes MUDr.…
Languages: Czech
Treatment highlights
- Skin assessment and protocol selection
- Topical numbing and cleansing
+3 more items in What's included
Rejuran full face (physician-applied polynucleotides): 9,880 Kč; package of 3 revitalisation courses 23,985 Kč; Rejuran with atraumatic needle from 6,940 Kč. Nurse-applied injector skin boosters: PN salmon DNA + hyaluronic acid face 6,900 Kč; face + neck + décolleté 8,990 Kč; 20% crosslinked HA skin booster 2 ml 6,900 Kč (2× 2 ml package 11,900 Kč).