Profhilo Bioremodelling

Profhilo is the original skin 'bioremodelling' injectable — one of the highest concentrations of pure, non-crosslinked hyaluronic acid on the market (64 mg in 2 ml). Injected at five standardised points per side of the face, it spreads through the tissue like honey rather than sitting as volume, intensely hydrating the skin and stimulating four types of collagen and elastin. The result over the standard two-session protocol is firmer, denser, glowing skin and a subtle tightening of early laxity — without changing face shape. AMEM also offers Profhilo Structura, a cannula-applied version that restores the superficial fat layer for cheek and lower-face support ('lipolifting'). Package pricing covers the full two-treatment protocol.

Profhilo (IBSA) created the 'bioremodelling' category: it is neither a filler nor classic mesotherapy, but an ultrapure thermally stabilised hyaluronic acid that disperses horizontally through the skin layers, acting as a slow-release reservoir that both hydrates and biologically activates the tissue. **How it differs from fillers:** Crosslinked fillers are gels engineered to hold shape and add volume in a specific spot. Profhilo is non-crosslinked — it flows and integrates across the treatment zone within 24 hours, so it cannot create lumps or change facial contours. Its job is biological: studies show stimulation of collagen types I and III plus elastin, improved skin elasticity and dermal thickness over the weeks following treatment. **The BAP technique:** Profhilo is injected at five anatomically mapped Bio Aesthetic Points per side of the face (or neck), chosen to maximise spread while avoiding vessels and nerves — making the treatment fast (around 15–30 minutes), low-risk and nearly painless, with only small temporary blebs at the injection points that settle within hours to a day. **Protocol:** Two sessions one month apart form one full course (package 14,900 Kč — saving versus single sessions at 8,900 Kč). Visible improvement in glow and hydration appears within days of the first session; firmness and elasticity build after the second. Maintenance is typically one session every 6 months. **Profhilo Structura (11,900 Kč; 2-pack 21,990 Kč):** the newer Structura formulation is applied by blunt cannula into the superficial fat compartment, where ageing causes deflation and descent. It restores the structural support of this layer — a 'lipolifting' effect for hollowing cheeks and early jowl shadowing — and pairs naturally with standard Profhilo for skin quality. **Best suited to:** clients 35+ with early laxity, dullness, crepey texture or 'tired' skin who want overall quality and firmness rather than added volume. Contraindications: pregnancy/breastfeeding, active skin infection or inflammation, known hypersensitivity to hyaluronic acid preparations.