

Type
Mesotherapy
Duration
30 min
What's included
5 deliverables in this treatment
- Skin assessment and protocol planning
- Profhilo 2 ml (64 mg HA) via the 5-point BAP technique per side
- Option of Profhilo Structura cannula lipolifting application
- Aftercare guidance
- Two-session package pricing for the standard protocol
Profhilo is the original skin 'bioremodelling' injectable — one of the highest concentrations of pure, non-crosslinked hyaluronic acid on the market (64 mg in 2 ml). Injected at five standardised points per side of the face, it spreads through the tissue like honey rather than sitting as volume, intensely hydrating the skin and stimulating four types of collagen and elastin. The result over the standard two-session protocol is firmer, denser, glowing skin and a subtle tightening of early laxity — without changing face shape. AMEM also offers Profhilo Structura, a cannula-applied version that restores the superficial fat layer for cheek and lower-face support ('lipolifting'). Package pricing covers the full two-treatment protocol.
About this treatment
Profhilo (IBSA) created the 'bioremodelling' category: it is neither a filler nor classic mesotherapy, but an ultrapure thermally stabilised hyaluronic acid that disperses horizontally through the skin layers, acting as a slow-release reservoir that both hydrates and biologically activates the tissue.
How it differs from fillers
Crosslinked fillers are gels engineered to hold shape and add volume in a specific spot. Profhilo is non-crosslinked — it flows and integrates across the treatment zone within 24 hours, so it cannot create lumps or change facial contours. Its job is biological: studies show stimulation of collagen types I and III plus elastin, improved skin elasticity and dermal thickness over the weeks following treatment.
Good to know
- Product
- Profhilo (IBSA) — 64 mg/2 ml non-crosslinked HA
- Technique
- 5-point BAP injection per side; Structura via cannula
- Protocol
- 2 sessions 1 month apart; maintenance ~every 6 months
- Downtime
- Small injection-point blebs settle within ~24 hours
- Effect
- Firmness, hydration, glow — no added volume
Who is this for?
Early skin laxity, crepey or dull skin, dehydrated complexion, clients wanting firmness without filler volume, neck and lower-face skin quality
Preparation required
Avoid alcohol and blood-thinning supplements 24–48 hours before to limit bruising. Arrive without makeup if possible. Expect small raised points at injection sites for up to a day. Plan the second session one month after the first for the full protocol.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
52 clinic reviews
From independent platforms
Clinical team
Plastic surgeon MUDr. Hana Skeřilová leads the surgical programme at the Zlín branch — she has worked in plastic surgery since 1995 (FNsP Ostrava-Poruba), headed the laser centre of the Institute of Medical Cosmetics in Ostrava from 2000, practised as an aesthetic plastic surgeon at well-known clinics in Prague and Brno, and is a member of the aesthetic surgery society. The corrective dermatology team includes MUDr.…
Languages: Czech
Treatment highlights
- Skin assessment and protocol planning
- Profhilo 2 ml (64 mg HA) via the 5-point BAP technique per side
+3 more items in What's included
Profhilo 2 ml syringe (64 mg non-crosslinked hyaluronic acid): 8,900 Kč per treatment; package of 2 treatments 14,900 Kč (the standard protocol is 2 sessions one month apart). Profhilo Structura — cannula lipolifting application: 11,900 Kč; Structura package of 2 treatments 21,990 Kč.
