Type
Mesotherapy
Duration
30 min
What's included
4 deliverables in this treatment
- Pre-treatment skin assessment and BAP protocol planning
- Full Profhilo session (2 mL syringe, 10 injection points per face)
- Post-injection cooling if required for bruising
- Treatment course plan (session 1 + session 2 schedule)
Profhilo at Skinity Clinic is the highest-concentration HA bioremodelling injectable currently available in Europe — a 64 mg/2 mL formulation of thermally stabilised hyaluronic acid that is not cross-linked in the traditional filler sense. Rather than creating volume or projection, Profhilo disperses through the tissue hydrating, tightening, and remodelling the skin architecture at the cellular level. MUDr. Martin Bortlík administers it using the BAP (bio-aesthetic points) protocol — five anatomically defined injection points per cheek — that distribute the product through the tissue's natural hydraulic pressure. The result is improved skin quality, elasticity, firmness, and a luminous skin tone that emerges progressively over 4–8 weeks as the four types of collagen and elastin stimulation take effect. The standard treatment is 2 sessions 4 weeks apart.
About this treatment
Profhilo (IBSA Farmaceutici Italia) is classified as a bioremodeller rather than a filler, reflecting its fundamentally different mechanism of action. Standard HA dermal fillers use chemical cross-linking (BDDE) to create a stable gel that occupies volume at the injection site. Profhilo, by contrast, uses a thermal NAHYCO® hybridisation process to create a stabilised hybrid cooperative complex of high- and low-molecular-weight HA without cross-linking…
Mechanism of action
Once injected, the HA complex exerts osmotic hydration of the surrounding extracellular matrix and stimulates four key types of collagen (I, III, IV, VII) and elastin production via fibroblast activation. Unlike conventional fillers that primarily occupy space, Profhilo improves the quality of the tissue it moves through — practitioners describe it as 'remodelling the scaffolding' rather than 'filling a cavity.'
Good to know
- Product
- Profhilo NAHYCO® hybrid HA complex (IBSA)
- Volume per session
- 2 mL (1 syringe, 10 points)
- Protocol
- 2 sessions × 4 weeks apart
- Results visible
- Progressive — full effect at 12 weeks
- Downtime
- None — small papules resolve in 2–6 hours
Who is this for?
Skin quality decline (laxity, dullness, crepiness), neck and décolletage rejuvenation, hydration, early-stage skin ageing, patients avoiding structural fillers
Preparation required
Avoid aspirin, NSAIDs, and fish oils for 5–7 days if medically safe. Arrive with clean skin. No active skin infections. Cold sore history — note in advance; antiviral prophylaxis may be recommended.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
The clinic is led by MUDr. Martin Bortlík, a graduate of Charles University (Univerzita Karlova) and the University of Defence (Univerzita Obrany), specialising in dermatology and aesthetic medicine. He brings extensive international clinical experience from Taiwan, Dubai, Switzerland, and the United States, and focuses on a 'full face approach' philosophy for both female facial contouring and male sculpting using…
Clinic-reported credentials
Languages: Czech, English
What clients say
"{"author":"Klara Maskova","date":"2025-12","source":"Google Reviews","text":"Absolutely positive experience. After many years of struggling, I finally found a doctor who is not only an expert but also incredibly human, fair and kind."}"
"{"author":"Simona Hanesova","date":"2025-11","source":"Google Reviews","text":"I can recommend Skinity Clinic to anyone looking for top aesthetic care. The treatment was completely painless."}"
Treatment highlights
- Pre-treatment skin assessment and BAP protocol planning
- Full Profhilo session (2 mL syringe, 10 injection points per face)
+2 more items in What's included
From 7,000 Kč per session. The standard Profhilo protocol is 2 sessions, 4 weeks apart (total from 14,000 Kč). Profhilo Body Kit (for neck, décolletage, or body areas) 22,500 Kč per kit. Maintenance session every 6 months recommended.