NAD+ IV Infusion

High-dose intravenous NAD+ (nicotinamide adenine dinucleotide) infusion delivered over two hours to support cellular energy metabolism, DNA repair, and NAD-dependent enzyme activity. One of the most research-backed interventions in longevity medicine.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, serving as the essential substrate for over 500 enzymatic reactions including those involved in mitochondrial energy production (the electron transport chain), DNA strand-break repair (via PARP enzymes), and the activity of sirtuins — a class of proteins heavily implicated in longevity, metabolic regulation, and stress response. NAD+ levels decline progressively with age — falling by approximately 50% between the ages of 40 and 60 — and this decline is now understood to contribute directly to age-associated declines in cellular energy, metabolic efficiency, and the capacity to repair DNA damage. Intravenous NAD+ administration raises plasma and cellular NAD+ concentrations more reliably than oral precursors (NMN or NR) because it bypasses intestinal conversion steps and first-pass liver metabolism. Studies in human subjects have demonstrated that IV NAD+ infusions produce measurable increases in whole-blood NAD+ levels within hours, with effects persisting for days to weeks after a series of infusions. Reported clinical effects include improved cognitive clarity, increased physical energy, reduced anxiety (via NAD's role in tryptophan metabolism), and improved sleep quality. At Aesthetify, the NAD+ infusion is administered slowly over two hours — a pace that minimises the chest tightness and nausea that can occur with faster infusion rates. The clinic's physicians conduct a pre-infusion assessment to confirm suitability and discuss protocol frequency (single sessions or a series of 3-5 infusions for those pursuing a structured longevity protocol). In-house blood analysis is available to baseline NAD+ status before and after a series. At €650 per infusion, Aesthetify's NAD+ pricing is in line with specialist longevity clinics across Europe. The combination of Charité-trained medical oversight, dedicated IV facilities, and the option to pair NAD+ infusions with aesthetic treatments makes this a distinctive offering in Berlin.