Food Intolerance Testing (IgG — 270+ Foods)

5P Medicine's food intolerance panel tests IgG antibody reactions to more than 270 foods, spices and additives — a far more extensive screen than standard IgE allergy tests which only catch immediate hypersensitivity reactions. IgG-mediated intolerances cause delayed, low-grade inflammation (typically hours to days after consumption) that can drive digestive symptoms, skin conditions, fatigue, headaches and chronic pain without an obvious food-symptom link. Results include a prioritised list of currently problematic foods, a roster of safe alternatives and a customised rotation diet plan. Patients with identified intolerances additionally receive a personalised cookbook with recipes that exclude their flagged foods.

Standard allergy testing detects IgE antibodies, which govern rapid hypersensitivity reactions (hives, anaphylaxis). Food intolerance, by contrast, involves IgG antibodies — a delayed immune response that can take four to seventy-two hours to manifest as symptoms. Because the reaction is slow and diffuse, patients rarely connect specific foods to their symptoms without systematic testing. 5P Medicine's IgG food intolerance panel covers more than 270 distinct antigens, including common grains (wheat, rye, spelt, corn), dairy proteins (casein, whey fractions), eggs, a wide range of meats, fish, vegetables, fruits, legumes, nuts, spices, preservatives and food additives. This breadth is important because many patients with gut dysbiosis have developed secondary sensitivities to multiple seemingly unrelated foods — a pattern that only becomes visible with a comprehensive panel. The test uses a venous blood draw. The serum is analysed using enzyme-linked immunosorbent assay (ELISA), which quantifies IgG antibody concentrations for each antigen and classifies the reaction as none, mild, moderate or strong. The resulting report lists every flagged food with its reactivity class and suggests tolerated alternatives within the same nutritional category. The clinical protocol that follows is based on an elimination and rotation strategy. Strong-reactivity foods are eliminated for a minimum of three months to allow intestinal inflammation to resolve and barrier integrity to improve. After this washout period, foods are reintroduced one at a time to gauge whether tolerance has been restored. A customised rotation diet plan (typically five to ten day cycles) then reduces the risk of developing new sensitivities by preventing repeated high-dose exposure to the same antigens. 5P Medicine includes a personalised cookbook with the results — a practical tool that replaces flagged ingredients with equivalents so patients can maintain a nutritious, varied diet during elimination. MUDr. Hora typically recommends combining food intolerance testing with gut microbiome analysis, since leaky gut driven by dysbiosis is often the root cause of acquired food sensitivities. Treating the microbiome simultaneously accelerates recovery and reduces the likelihood of new intolerances developing.