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Comprehensive breath test to detect small intestinal bacterial overgrowth (SIBO).

Additional Information

Bacterial overgrowth in the small intestine can cause malabsorption of key nutrients and symptoms of irritable bowel syndrome. This test measures hydrogen and methane gas levels in breath samples after ingesting glucose and lactulose. It helps diagnose SIBO and assess oro-caecal transit time (OCTT). Early detection and treatment can improve nutrient absorption, alleviate symptoms, and potentially impact conditions like fibromyalgia and chronic fatigue syndrome.

Biomarkers Tested (5)

Hydrogen increase over baseline by 90 mins (ppm)

Bacteria in the small intestine produce hydrogen and methane when exposed to glucose. SIBO may be diagnosed with a rise in breath hydrogen of >20ppm in the first 90 minutes.

Peak methane excretion over baseline (ppm)

Bacteria in the small intestine produce hydrogen and methane gas when exposed to glucose. SIBO may be diagnosed with a rise in breath methane of >10ppm above the baseline.

Hydrogen increase over baseline by 90 mins (ppm)

Bacteria in the small intestine produce hydrogen and methane when exposed to glucose. SIBO may be diagnosed with a rise in breath hydrogen of >20ppm in the first 90 minutes.

Peak methane level at any point (ppm)

Bacteria in the small intestine produce hydrogen and methane gas when exposed to lactulose. Methane excretion is indicated by >10ppm sustained rise upon lactulose challenge.

OCTT (oro-caecal transit time) (minutes)

Normal OCTT (the time it takes for lactulose to pass through the gut) in healthy adults is approx 60-120min.

SIBO Check - Glucose + Lactulose

Additional Information

Biomarkers Tested (5)

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Test Details