Cortisol Awakening Response (CAR) by i-Screen

Saliva test providing information on cortisol rhythms and stress response.

Additional Information

The cortisol awakening response (CAR) is a natural increase in cortisol upon waking. Normally, cortisol is highest in the morning and gradually decreases throughout the day. The CAR is a sharp increase peaking around 30 minutes after waking. This increase helps mobilize energy. The CAR is linked to stress response and various health outcomes, including depression, anxiety, and chronic fatigue. It's also associated with sleep quality; disrupted sleep may affect the CAR. This test helps understand your body's stress response and cortisol patterns.

Biomarkers Tested (11)

Cortisol Morning (on waking) (µg/dL)

Cortisol levels are generally high in the morning upon waking, with an increase of up to 50% in the first half an hour after waking. This is known as the ‘cortisol awakening response’.

Cortisol Morning (+30 mins) (µg/dL)

Cortisol levels are generally high in the morning as we wake from a prolonged period of sleep, with an increase of up to 50% in the first half an hour after waking. This is known as the ‘cortisol awakening response’.

Cortisol Morning (+30 mins) (µg/dL)

Cortisol Profile, Total CAR (µg/dL)

Total CAR measures the total amount of cortisol released during the first 30-45 mins after waking, which includes both the initial peak and subsequent decline in cortisol.

DHEAS (µg/dL)

Dehydroepiandrosterone sulfate (DHEAS) is a hormone produced by the adrenal glands that serves as a precursor to sex hormones. Abnormal levels can indicate adrenal or endocrine disorders.

Cortisol/DHEAS Ratio CAR

A high cortisol to DHEA ratio has been linked to increased inflammation, suppressed immune function, hyperglycaemia, as well as impaired detoxification, skeletal health and cognitive function.

CAR Rise Response (µg/dL)

The cortisol awakening response (CAR) is a period of increased cortisol secretory activity initiated by morning awakening and typically peaking between 30 and 45min post awakening

CAR Decline Response (µg/dL)

A significant burst of cortisol in the immediate awakening period (within 20 min) followed by a steep decline in levels has been shown to be a better measure of CAR and health status.

Cortisol Midday (ng/mL)

As the day progresses cortisol levels naturally begin to drop in a fairly constant and regular fashion that is termed a diurnal rhythm, ending up as low in the late evening.

Cortisol Afternoon (ng/mL)

As the day progresses cortisol levels naturally begin to drop in a fairly constant and regular fashion that is termed a diurnal rhythm, ending up as low in the late evening.

Cortisol Evening (ng/mL)

Cortisol levels drop very low in the evening and during the early phase of sleep which allows the body to keep a regular sleeping pattern.

Cortisol Awakening Response (CAR)

Additional Information

Biomarkers Tested (11)

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Test Details