Intestinal Permeability (Leaky Gut) Check by i-Screen

Urine test to assess intestinal permeability.

Additional Information

This test measures levels of lactulose and mannitol, which are synthetic sugars. Lactulose is a large molecule, and only small amounts should be absorbed by the gut and excreted in the urine. Mannitol is a small molecule, readily absorbed and excreted. A high ratio of lactulose to mannitol indicates increased intestinal permeability ('leaky gut'). This test helps identify gut lining damage, which can lead to inflammation and other health issues. It's useful for those experiencing digestive problems or autoimmune conditions.

Biomarkers Tested (3)

Lactulose Recovery (mg/dL)

Lactulose is a 'large' molecule, and only small levels should be absorbed by the gut and excreted into the urine.

Mannitol Recovery (mg/dL)

Mannitol is a 'small' molecule which is readily absorbed by the gut and subsequently excreted into the urine.

Recovery Ratio (Lactulose/Mannitol)

Where 'leaky gut' is present, the large synthetic sugar molecules can penetrate the gut lining and are recovered in the urine, resulting in a high recovery ratio.

Intestinal Permeability (Leaky Gut) Check

Additional Information

Biomarkers Tested (3)

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Test Details