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Blood Testing Laboratory
Quest Diagnostics

Autoimmune Screening Test (ANA with Reflex)

Detect autoantibodies in your blood related to various autoimmune diseases to help you and your healthcare provider determine next steps.

12 Biomarkers
$118.00
$112.00

Detect autoantibodies in your blood related to various autoimmune diseases to help you and your healthcare provider determine next steps.

Additional Information

This test first checks for ANAs in your blood to help detect if an autoimmune disease is present. If ANAs are found, a series of more specific tests will be performed until autoantibodies associated with specific diseases are detected. This may include up to five rounds of testing on your provided sample. The test helps identify the presence of autoimmune diseases and guides further medical action. Early detection is crucial for managing autoimmune conditions effectively. Understanding your autoantibody profile can help you and your doctor make informed decisions about your health.

Biomarkers Tested (12)

Tin (NA)
NA
NA (µmol/L)
NA
Sm/RNP (Positive/Negative)
Antibodies to Sm/RNP (Smith/ribonucleoprotein) are highly specific for SLE.
Anti-RNP antibodies (NA)
Marker for mixed connective tissue disease (MCTD).
Osmolality (mOsm/kg)
Osmolality measures the concentration of dissolved particles in the blood, indicating hydration status.
Tin (NA)
NA
Interferon-Gamma Release Assay (IGRA) (pg/mL)
Measures the cell-mediated immune (CMI) response to T-cells to detect Mycobacterium tuberculosis bacteria. Does not differentiate between latent TB infection and TB disease.
SSB (Positive/Negative)
Anti-SSB (La) antibodies are associated with Sjögren's syndrome and SLE.
Scl-70 (Positive/Negative)
Anti-Scl-70 (topoisomerase I) antibodies are highly specific for systemic sclerosis.
Anti-Jo-1 (NA)
Marker for Polymyositis.
Ribosomal P (Positive/Negative)
Antibodies to ribosomal P proteins are associated with various autoimmune diseases.
Centromere B (Positive/Negative)
Anti-centromere B antibodies are associated with CREST syndrome (a form of systemic sclerosis).

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Test Details

Sample Type
Blood (Venous)
Fasting Required
Not required
Results Time
5 days
Price
$118.00 Includes a $6.00 Physician Service Fee
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